Liberia’s health authorities have raised fresh concerns over the continued spread of Mpox across the country, confirming more than 2,400 suspected infections since the start of the outbreak.
Chief Medical Officer Dr. Catherine T. Cooper announced that a total of 2,447 suspected cases have been recorded across all 15 counties, signaling sustained community transmission. Addressing a press conference in Monrovia, she disclosed that the Ministry of Health (MoH) and the National Public Health Institute of Liberia (NPHIL) are implementing a nationwide containment strategy focused on enhanced surveillance, vaccination, treatment, and public education.
According to the latest Situation Report (#87), 2,309 samples have been tested, out of which 1,308 cases were confirmed positive, representing a national positivity rate of 56.6%. The outbreak has so far spread to 65 of Liberia’s 98 health districts, underscoring the urgency of the government’s ongoing response.
Currently, 148 active cases are being monitored across infectious disease hospitals, isolation centers, and home-based care facilities. Montserrado County remains the epicenter, accounting for 57% of all active cases, followed by Nimba (18%), Margibi (7%), Grand Bassa (5%), and Grand Kru (4%). Other counties collectively contribute less than 2% of the total.
Despite the scale of infection, Dr. Cooper revealed that 1,154 patients have fully recovered, while six deaths have been recorded, a case fatality rate of 0.5%. She attributed the relatively low death rate to early case detection, improved management systems, and ongoing community sensitization efforts.
Strengthening the National Response
Health authorities, in collaboration with international partners, have unveiled an ambitious 90-day response plan aimed at curbing transmission between November 2025 and January 2026.
Key objectives include:
• Detecting and investigating at least 90% of suspected cases within 48 hours;
• Ensuring all samples are tested with results delivered within two days;
• Zero preventable deaths through enhanced intensive care, rapid diagnostics, and clinical refresher training;
• Administering all 42,720 vaccine doses to high-risk populations by January 2026;
• Achieving 80% nationwide awareness on prevention, early symptom reporting, and safe sexual practices.
Vaccination Rollout
Liberia will launch a ring vaccination campaign beginning this month in Montserrado and other hotspot counties, expanding nationwide in December 2025 through February 2026. The campaign targets individuals aged 18 and above to prevent further spread.
In September 2025, Liberia received 42,720 doses of Mpox vaccines through a global consortium including the U.S. CDC, Africa CDC, GAVI, UNICEF, and the Coalition for Epidemic Preparedness Innovations (CEPI).
Public Appeal
Dr. Cooper described the current phase as “a critical turning point” in Liberia’s Mpox fight, stressing that collective action is vital.
“Without bold measures, Mpox transmission will continue to escalate, placing lives, health systems, and communities at risk,” she warned.
She urged community leaders, civil society, and citizens to actively support awareness drives and vaccination efforts.
“Your support is crucial to ending this outbreak,” Dr. Cooper appealed.
The government has reiterated its commitment to maintaining transparency, timely updates, and robust collaboration with both local and international partners as Liberia works to bring the Mpox outbreak under control.
